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Evaluation of physiological metabolic changes in dogs 60 days of age exposed to direct oxygen tracheostomy
Evaluation of physiological metabolic changes in dogs 60 days of age exposed to direct oxygen tracheostomy
Rosa E. Soriano-Rosales 1 
, Beatriz E. Pérez-Guillé 1 , Emilio Arch-Tirado 2 , Antonio Verduzco-Mendoza 3, Pamela Sánchez-Pérez 4
1 Translational Research Center, Instituto Nacional de Pediatría, Secretaría de Salud. Mexico City, Mexico; 2 Centro Neurológico, Centro Médico ABC, Sede Santa Fe, Ciudad de México, México; 3 División de Biotecnología-Bioterio y Cirugía Experimental, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra. Ciudad de México, México; 4 Centro de Investigación Traslacional, Instituto Nacional de Pediatría, Ciudad de México, México
*Correspondence: Beatriz E. Pérez-Guillé. Email: bettyepg@yahoo.com
Abstract
Background: Blood gas analysis is used to monitor gas exchange and homeostasis in acid-base balance.
Objective: To evaluate changes in blood gases with tracheostomy puppies directly exposed to oxygen. Twelve puppies of 60 days of age were used, where each one received a tracheotomy and 10 cm from it, a tracheal tube with an O2 concentration of 100% at 3 liters was placed; venous samples were taken before anesthesia, with an exposed trachea, closing the tracheostomy and post-anesthesia recovery.
Methods: We used a blood gas analyzer. Statistics were done with t Student’s paired, as box and standard error charts were made. The pO2 rises and falls along the four measurements, pCO2 values have a sinusoid tendency. The values of pCO2 and pO2 behave inversely during the first two blood takes; there were variations in the values of pO2 and pCO2, SO2 and TCO2 throughout surgery.
Results: Glucose values present a bell-shaped behavior and lactate a U-shaped one. The pH and HCO3 showed no significant differences. There were statistical variations for sodium, potassium, calcium, and hematocrit.
Conclusions: The dog is a good animal model for gas exchange in tracheal surgery studies.
Keywords: Blood gases. Trachea. Surgery. Dogs. Oxygen.
