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Thromboprophylaxis with direct oral anticoagulants in bariatric surgery: narrative review
Thromboprophylaxis with direct oral anticoagulants in bariatric surgery: narrative review
Darwin G. Perea-Martínez 1 
, Byron A. Moreno-Muñoz 2 , Andrea J. Contreras-Ojeda 3 , Juan P. Torres- Romero 4 , Edwin A. Gallego-González 5 , Manuel A. Jaramillo-Acosta 6 , Santiago Gallo-Ramírez 7 , Michael Ortega-Sierra 8
1 Departamento de Medicina, Universidad de Santander, Bucaramanga, Colombia; 2 Departamento de Medicina, Universidad de Nariño, Pasto, Colombia; 3 Departamento de Medicina, Universidad Industrial de Santander, Bucaramanga, Colombia; 4 Departamento de Medicina, Universidad de Pamplona, Pamplona, Colombia; 5 Departamento de Medicina, Institución Universitaria Visión de las Américas, Pereira, Colombia; 6 Departamento de Medicina, Universidad del Quindío, Armenia, Colombia; 7 Departamento de Medicina, Universidad de Antioquia, Medellín, Colombia; 8 Universidad Centroccidental Lisandro Alvarado, Hospital Central Antonio María Pineda, Barquisimeto, Venezuela
*Correspondence: Michael Ortega-Sierra. Email: mortegas2021@gmail.com
Abstract
Bariatric surgery is an increasingly common surgical procedure, considering its scope and impact on numerous pathological conditions. The frequency of post-intervention complications is a topic of interest in clinical practice. Post-intervention thromboembolic risk is one of the most important considerations during the recovery from bariatric surgery. Various therapies can be used to manage this thromboembolic risk, among which oral direct anticoagulants stand out. Despite the overall effectiveness and safety of this pharmacological group, several authors have raised potential differences to consider in the postoperative scenario of bariatric patients. To date, meta-analyses have only evaluated observational studies to answer this question. Therefore, recognizing the importance of understanding the therapeutic performance of oral direct anticoagulants in one of the increasingly common interventions, the objective of this review is to analyze the performance of oral direct anticoagulants and the risk of thromboembolism after bariatric surgery, based on the most recent evidence.
Keywords: Anticoagulants. Thromboembolism. Bariatric surgery. Risk. Therapeutics.
