Impact of obesity on COVID-19 severity: a Mexican experience

Introduction The coronavirus disease-2019 (COVID-19) pandemic has represented a global challenge. Since the severity of the disease is highly variable, it is very important to identify people with the highest vulnerability to acquire the disease, as well as the development of serious illness and death. Initial data showed that elderly individuals, as well as people […]

Clinical characteristics of ovarian cancer in children under 17 years of age

Introduction Ovarian cancer is the fifth most common neoplasm in women. The International Agency on Cancer reported 97 new cases in Mexico in 2020, between the ages of 0 and 19 years1. The ovary presents a wide range of malignant neoplasms, divided into epithelial cancer, germ cell tumors, stromal tumors of the sexual cords, and […]

Prediabetes and hepatitis C virus with insulin resistance

Introduction According to the World Health Organization (WHO) 2024 Global Hepatitis Report, the number of lives lost due to viral hepatitis is increasing. The WHO sounds alarm on viral hepatitis infections claiming 3500 lives each day1. This disease is the second leading infectious cause of death globally with 1.3 million deaths per year, the same […]

Can you really combat lung inhomogeneity with alveolar stability?

Introduction Answering the question set in our title comes as no easy task if we consider that the lung suffers from non-linear deformation even during normal breathing1. This becomes even harder when we consider the biomechanic factors that mechanical ventilation (MV) imposes on the lung. Such insults such as barotrauma (alveolar air leak due to […]

Current developments in the management of post-operative nausea and vomiting

Introduction Post-operative nausea and vomiting (PONV) is currently one of the most common adverse events after surgery. It is an unpleasant experience for the patient with clinical repercussions such as incisional pain, hematoma formation, suture dehiscence, esophageal rupture, bilateral pneumothorax, and delayed discharge from post-anesthesia care units (PACU). This series of complications delays hospital discharge […]

Corneal neurotization as treatment for patients with neurotrophic keratopathy and facial palsy

Introduction Neurotrophic keratopathy is a degenerative corneal disease induced by damage to the trigeminal nerve. Reduced corneal sensitivity (also called corneal anesthesia) leads to poor epithelial healing, generating epithelial keratopathy, ulceration, and corneal perforation1, 2. In addition, there is an alteration in the production of tears, which leads to greater corneal damage3. The most common […]

Spinal and sciatico-popliteous block in patient with systemic lupus erythematosus subjected to ankle arthrodesis

Introducción El lupus eritematoso sistémico (LES) es una enfermedad autoinmune caracterizada por la pérdida de la autotolerancia y formación de autoantígenos nucleares y complejos inmunes que resultan en inflamación de múltiples órganos. A pesar de muchos avances en el tratamiento y mejores diagnósticos, el LES continúa causando una morbilidad sustancial y mortalidad prematura. Las estrategias […]

Multifocal motor neuropathy

Introducción La neuropatía motora multifocal (NMM) es un trastorno único que se presenta como una mononeuropatía múltiple motora pura asimétrica de las extremidades superiores, de distribución multifocal con atrofia a menudo prominente1. Es una enfermedad rara, con una prevalencia de 0.2 a 2 por 100,000 habitantes2. La NMM afecta más comúnmente a los hombres, con […]

Sincipital encephalocele as infrequent neural tube defect

Introduction An encephalocele is defined as the herniation of intracranial content through a bony defect in the skull (bifid cranium). This condition is part of the disorders involving the fusion of midline structures of the primitive neural tube during the first 3 weeks of gestation1,2, where central nervous system malformations make up approximately one-third of […]