Cerebral toxoplasmosis in children

Cerebral toxoplasmosis in children

Alejandro O. Amador-Pérez 1 , Yadira B. Melchor-Vidal 1, Alberto Olaya-Vargas 1, Sara M. Rivera-Velásquez 1, Michelle Y. Segundo-Zavala 1, Jesús G. Ponce-Cruz 1 , César Cárdenas-Pérez Gallardo 1

1 Servicio de Pediatría, Centro Médico ABC, Ciudad de México, México

*Correspondence: Alejandro O. Amador-Pérez. Email: pediarevision@gmail.com

Abstract

Acute lymphoblastic leukemia is a malignant disease affecting children, especially those aged 2-5 years, with a higher frequency in males. It is characterized by the proliferation of lymphoid progenitor cells in the bone marrow, blood, and extramedullary sites. Symptoms are nonspecific, with bone marrow failure and possible central nervous system involvement. Treatment can lead to complications such as neutropenia, immunosuppression, and infections by opportunistic microorganisms (fungi, mycobacteria, viruses, parasites). Toxoplasmosis, caused by Toxoplasma gondii, is a serious infection in immunocompromised individuals. Prompt detection and treatment are crucial for improving prognosis.

Keywords: Childhood leukemia. Neurological disorder. Central nervous system. Infection. Immunosuppression. Toxoplasma gondii.

Contents

Content available only in Spanish.

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Content available only in Spanish.

    DOI not available