Stereoelectroencephalography and focal radiofrequency ablation for the management of drug-resistant epilepsy: first case in Mexico




Enrique de Font-Réaulx, Departamento de Cirugía de Epilepsia, Centro Neurológico, Centro Médico ABC, Ciudad de México, México
Javier Terrazo-y Lluch, Unidad de Neurocirugía Pediátrica, Cirugía de Epilepsia, Centro Neurológico, Centro Médico ABC, Mexico City, Mexico
Miguel A. Collado-Corona, Editor en Jefe, Anales Médicos. Centro Neurológico, Centro Médico ABC Santa Fe, Ciudad de México, México
Paul Shkurovich-Bialik, Unidad de Neurofisiología y Clínica de Epilepsia, Cirugía de Epilepsia, Centro Neurológico, Centro Médico ABC, Mexico City, Mexico
Luis G. Díaz-López, Unidad de Neuroanestesiología, Instituto Nacional de Neurología y Neurocirugía “Manuel Velasco Suárez”, Centro Neurológico, Centro Médico ABC, Mexico City, Mexico
Ernesto Ramírez-Navarrete, Unidad de Neurocirugía Pediátrica, Cirugía de Epilepsia, Centro Neurológico, Centro Médico ABC, Mexico City, Mexico
Israel Romero-Rangel, Unidad de Neurocirugía. Centro Neurológico, Centro Médico ABC, Mexico City, Mexico
Adalberto González-Astiazarán, Departamento de Neurocirugía Pediátrica, Centro Neurológico, Centro Médico ABC, Ciudad de México, México


The SEEG was invented in France in the late 1950s. Thanks to new imaging technologies and STX it has improved dramatically. This method makes it possible to record electrical activity outside the operating room through intracerebral electrodes implanted in the cortical and subcortical structures predefined by STX. With the ictal and interictal information, complemented with electrical stimulation applied in the contacts of the selected implanted electrodes, a precise surgical plan is established in cases when required. This bidirectionality of the SEEG electrodes can be used to make RF-SEEG lesions. This is the first case of DRE treated with SEEG/RF-SEEG in Mexico at the ABC Medical Center. Objectives: to safely and effectively implant SEEG electrodes to obtain ictal and interictal records in patients with DRE and make a surgical plan to control seizures.This is the case of an adult with DRE. We implanted the first 9 SEEG electrodes in Mexico through STX and recorded intracerebral activity for 5 continuous days. By analyzing the ictal and interictal SEEG recording obtained and doing functional mapping and seizure induction by electrical stimulation, we performed RF-SEEG lesions at the ictal onset site. The patient was discharged without morbidity. Having SEEG/RF-SEEG technology available defines us as an advanced epilepsy surgical center to safely and effectively register selected cases of DRE to establish surgical plans according to the highest current international standards.



Keywords: Drug-resistant epilepsy. Stereoelectroencephalography. SEEG-guided radiofrequency ablation.