Author: Zury López

Chronic activation of histamine H3 receptors reduces L-dopa-induced dyskinesias in a model of hemiparkinsonian rats with 6-hydroxydopamine lesions

Introduction Parkinson’s disease (PD) is a central clinical motor syndrome accompanied by neurodegeneration of the substantia nigra pars compacta (SNc) and the deposition of synuclein.1 Its prevalence is estimated at 1% among individuals over 60 years of age.2 For symptomatic treatment, systemic administration of L-3,4-dihydroxyphenylalanine (L-Dopa) is commonly used owing to its efficacy. Prolonged L-Dopa […]

Burnout syndrome and associated factors among oncology nurses in a Mexican tertiary care hospital: a cross-sectional study

Introduction Nursing personnel constitute one of the most important pillars of healthcare systems, as they provide direct and continuous patient care throughout all stages of the healthcare process, particularly in oncology services. Their work requires not only solid professional training but also a high degree of emotional commitment1,2. Working conditions, such as prolonged shifts, excessive […]

Neuroprotective effect of reboxetine on sensorimotor function and norepinephrine levels in a model of intracerebral hemorrhage

Introduction Stroke is a clinical syndrome characterized by an acute neurological deficit of vascular origin.1 Globally, it represents the second leading cause of death and the third leading cause of combined death and disability.2 Hemorrhagic etiology has a critical clinical impact; specifically, intracerebral hemorrhage (ICH) accounts for 28.8% of all incident cerebrovascular events2 and is […]

Clinical characteristics and survival of obstetric patients with cerebrovascular disease in a tertiary referral center

Introduction During pregnancy and the puerperium, the maternal organism undergoes a series of complex physiological adaptations that affect multiple systems, with the goal of sustaining fetal development and preparing the mother for childbirth and lactation. These changes, although indispensable for reproductive success, also predispose the pregnant woman to various medical complications and pathologies.1,2 Among the […]

Comparative analysis of active range of motion in patients with proximal humerus fractures treated with osteosynthesis versus shoulder arthroplasty

Introduction Proximal humerus fractures (PHFs) are a common injury, particularly in the older age group, and represent a significant portion of orthopedic trauma cases. These fractures account for approximately 10% of all fractures in individuals aged 65 and older.1,2 With the increase in life expectancy and aging populations worldwide, the incidence of PHFs should increase […]