Patient self-inflicted lung injury and ultraprotective mechanical ventilation: a narrative review

Introduction Nowadays, it is recognized that patients receiving mechanical ventilation (MV) may actively contribute to the progression of lung injury through their own respiratory effort. This phenomenon, termed patient self-inflicted lung injury P-SILI, proposes that strong inspiratory efforts, patient-ventilator asynchronies, and markedly negative intrathoracic pressures can intensify injury in an already vulnerable lung parenchyma1. Several […]