Progression-free survival in patients with castration-resistant prostate cancer treated with anti-androgens in a tertiary care hospital in Puebla, Mexico

Introduction Prostate cancer is the 2nd most frequent malignant neoplasm among men worldwide. In 2022, the International Agency for Research on Cancer reported 10,311,610 cases globally, with an incidence rate of 14.2% and a mortality rate of 9.6%. In Mexico, of 25,000 reported cases, 7,500 resulted in death1,2. Early detection impacts prognosis; therefore, measurement of […]

Patient self-inflicted lung injury and ultraprotective mechanical ventilation: a narrative review

Introduction Nowadays, it is recognized that patients receiving mechanical ventilation (MV) may actively contribute to the progression of lung injury through their own respiratory effort. This phenomenon, termed patient self-inflicted lung injury P-SILI, proposes that strong inspiratory efforts, patient-ventilator asynchronies, and markedly negative intrathoracic pressures can intensify injury in an already vulnerable lung parenchyma1. Several […]